2019 ART Clinical Guidelines for the Management of HIV in Adults, Pregnancy, Adolescents, Children, Infants and Neonates
South Africa is committed to attaining the UNAIDS 909090 targets to control the HIV epidemic through quality comprehensive health services and use of highly effective antiretroviral treatment (ART). The principal goal of ART is to attain and maintain viral suppression, which will decrease morbidity and mortality from HIV as well as improve the quality of life for clients living with HIV.
The 2019 HIV clinical guidelines have been revised to include a new formulation of the fixed dose combination (FDC) of Tenofovir (TDF) 300 mg + Lamivudine (3TC) 300 mg + Dolutegravir (DTG) 50 mg (TLD) for all eligible adults, adolescents and children over the age of 10 years and weighing 20 kg or more. This document is an abridged version of the Consolidated ART Guideline, intended to serve as a quick reference guide and job aid for healthcare workers. It intends to:
- Provide guidance on initiating naïve clients on DTG-containing regimens
- Provide guidance on switching existing clients on ART to DTG-containing regimens
- Highlight critical areas for the provision of integrated ART, TB and family planning services
- Provide guidance on second and third line regimens in the era of DTG