Guidelines for the Prevention and Containment of Antimicrobial Resistance in South African Hospitals (2019)
These guidelines form part of efforts to institutionalise the prevention and containment of antimicrobial resistance (AMR) in health care facilities in South Africa, as outlined in the
Antimicrobial Resistance Strategic Framework and Implementation Plan. The focus of these guidelines is on two interrelated aspects of prevention of healthcare associated infections (HAIs) and their spread; and the application of antimicrobial stewardship (AMS) practices at hospital level. They aim to serve as a practical, step-by-step or ‘how-to’ guide, addressing the infection prevention and AMS components of a robust response in a hospital. They draw on evidence from various international guidance documents and standards for interventions that have been shown to be successful in infection prevention and AMS programmes.
These interventions have been customised to the South African hospital setting based on local experiences in the public and private health sectors. This was done through a series of workshops and requests for comment involving country-level experts. The focus of the guidelines will be on prevention of HAIs and stewardship of antibiotics used to
treat bacterial infections other than tuberculosis, however the suggested interventions can be applied equally to antifungals as they share the same stewardship principles. National guidelines already exist for the management of multi drug resistant tuberculosis and HIV. The guidelines are intended for use by a multidisciplinary cadre of healthcare
professionals – doctors, nurses, pharmacists, microbiologists, and infection prevention and control (IPC) practitioners, in their day-to-day management of AMR in a hospital setting.